TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype [organoids]
The aim of this study was to determine the effects of TGFβ at the premalignant stage of CRC development. Organoid cultures were isolated from normal colon and from tubular adenomas. One normal colon culture was genetically engineered using the CRISPR-Cas9 system to carry the BRAFV600E mutation.
Cancer Type: Colorectal Cancer
GPL: 13158
Number of Genes with Data: 978
Number Observations: 20
Number Outputs: 1
Imbalanced Ratio: 1
Default Task: Classification