Induction of ER stress in HCT116 colon cancer cells

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To investigate the role of p53 and DICER in the induction of ER stress, wildtype, p53 knockout or DICER mutant HCT116 colon cancer cells were treated with the ER stress inducers tunicamycin or brefeldin A for 24 hours. Microarray analysis was used to determine changes in gene expression associated with the induction of ER stress, and to compare this induction in wildtype, p53 knockout or DICER mutant HCT116 colon cancer cells

Cancer Type: Colon Cancer

GPL: 570

Number of Genes with Data: 978

Number Observations: 27

Number Outputs: 2

Imbalanced Ratio: 1

Default Task: Classification