Expression data for primary localized prostate cancer versus castration-resistant bone metastatic prostate cancer

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We compared 22 primary Pca (hormone-dependent) versus 29 metastatic Pca (CRPC). The expression of genes related to cell cycle, proliferation, DNA synthesis, and androgen metablism are significantly increased in CRPC group. The expression of AR-stimulated genes were partially reactivated. TMPRSS2-ERG fusion status was determined for the samples by PCR. The expression of ERG was highly increased in fusion positive versus negative.

Cancer Type: Prostate Cancer

GPL: 96

Number of Genes with Data: 906

Number Observations: 55

Number Outputs: 2

Imbalanced Ratio: 0.137931034

Default Task: Classification