Response prediction to neoadjuvant chemotherapy

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We investigated whether we could identify gene expression profiles in initial core biopsies of breast cancer samples that would permit to a) predict a clinically meaningful response to Epi/Doc in terms of tumor size reduction, b) predict a profound reduction in intratumoral Ki67 protein expression, and c) predict an in vitro response to Epi/Doc in the ATP-TCA.

Cancer Type: Breast Cancer

GPL: 96

Number of Genes with Data: 978

Number Observations: 22

Number Outputs: 3

Imbalanced Ratio: 0.833333333

Default Task: Classification