Expression data from epithelial cells during the process of multistep pancreatic carcinogenesis
The host antitumor immunity changes drastically during carcinogenesis. Intraductal papillary-mucinous neoplasm (IPMN) of the pancreas is a precursor lesion of pancreatic cancer and progresses according to adenoma-carcinoma sequence. We found that the host antitumor immune reaction changes from an immune response to immune tolerance between intraductal papillary-mucinous adenoma (IPMA) and intraductal papillary-mucinous carcinoma (IPMC). In order to determine molecules affecting intraepithelial DC infiltration in IPMNs during multistep carcinogenesis, we examined the gene-expression profiles of entire transcripts of neoplastic cells at different stages.
Cancer Type: Pancreatic Cancer
GPL: 570
Number of Genes with Data: 978
Number Observations: 22
Number Outputs: 1
Imbalanced Ratio: 0.428571429
Default Task: Classification