Clinical significance of gene signature generated from the grade of tumor budding in colorectal cancer
Tumor budding is a definite prognostic marker, but does not always show favorable reproducibility. We developed a new molecular signature related to tumor budding levels, a microscopic finding of dedifferentiation, using RNA extracted from the whole tissue section and disclosed its relevance to a high recurrence risk using an inhouse dataset and independent public datasets.
Cancer Type: Colorectal Cancer
GPL: 570
Number of Genes with Data: 978
Number Observations: 91
Number Outputs: 3
Imbalanced Ratio: 0.654545455
Default Task: Classification