Gene expression differences between adenocarcinoma and squamous cell carcinoma in human NSCLC
Non-small cell lung cancer (NSCLC) can be classified into the major subtypes adenocarcinoma (AC) and squamous cell carcinoma (SCC) subtypes. Although explicit molecular, histological and clinical characteristics have been reported for both subtypes, no specific therapy exists so far. However, the characterization of suitable molecular targets holds great promises to develop novel therapies in NSCLC. In the present study, global gene expression profiling of 58 human high grade NSCLC specimens revealed large transcriptomic differences between AC and SCC subtypes: More than 1.700 genes were found to be differentially expressed. Keywords: disease subtype analysis
Cancer Type: Lung Cancer
GPL: 570
Number of Genes with Data: 978
Number Observations: 58
Number Outputs: 1
Imbalanced Ratio: 0.45
Default Task: Classification