Fibroblast growth factor receptor 3 depletion effect on bladder cancer cell line RT112

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Analysis of bladder cancer cell line RT112 subjected to doxycycline-inducible, shRNA knockdown of FGFR3. Knockdown of FGFR3 in RT112 cells significantly attenuates tumor growth in vitro and in vivo. Results provide insight into the molecular mechanisms underlying FGFR3-driven bladder cancer.

Cancer Type: Bladder Cancer

GPL: 570

Number of Genes with Data: 940

Number Observations: 24

Number Outputs: 1

Imbalanced Ratio: 1

Default Task: Classification