Proteasome inhibitor Bortezomib or proteasome subunit knockdown effect on MCF7 breast cancer cells

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Analysis of MCF7 cells stimulated with bortezomib or depleted of PSMB3 or PSMB5. Proteasome inhibition can regulate estrogen-induced transcription. Results provide insight into mechanisms by which proteasome inhibition influences ERα function and into improved strategies for breast cancer treatment

Cancer Type: Breast Cancer

GPL: 14010

Number of Genes with Data: 957

Number Observations: 21

Number Outputs: 1

Imbalanced Ratio: 0.75

Default Task: Classification